About the study

Why this study is important?

Healthcare-associated infections (HAIs) are acquired as a direct or indirect result of healthcare. Infections associated with healthcare are not inevitable, and prevention programmes have been successful at reducing the incidence of some HAIs. In Australia, we have estimated 160,000 patients contract a HAI annually. – one ten patient today have an infection acquired in hospital.  Non-ventilator hospital associated pneumonia (HAP) is the most common type of HAI, accounting for approximately one third of these infections, with an estimated 50,000 patients affected each year in Australian public hospitals alone. HAP is associated with increased length of stay in hospital, increased morbidity, mortality, and healthcare costs.Approximately 19% of patients with HAP require transfer into an intensive care unit (ICU), with mortality reported at 18%. Patients with HAP are eight times more likely to die in hospital than similar patients without HAP.

About the study

Our study will:

  • Evaluate the effectiveness and cost-effectiveness of the intervention
  • Develop educational and digital resources and evaluate these as part of the trial
  • Estimate excess length of stay in hospital associated with HAP
  • Describe the patient’s experience of a having a HAP
  • Understand the clinician’s experience of implementing the intervention
  • Assess the impact of HAP on quality of life

The study phases

Our study consists of three phases, summarised below.

Phase 1

In this phase we will:

  • conduct focus groups and surveys with clinicians to understand current practice, knowledge, barriers/enables and beliefs about pneumonia prevention.
  • co-design educational and digital resources based on outcomes from the previous point

Phase 2

In this phase we will:

  • conduct multi-centre RCT to evaluate the impact of increasing the quality and frequency of oral care on the incidence of pneumonia in hospitalised patients
  • evaluate educational and digital resources
  • evaluate the cost-effectiveness of the intervention
  • estimate excess attributable length of stay in hospital associated with HAP
  • describe the patient experience of having HAP and the impact on quality of life

Phase 3

In this phase we will:

  • redesign resources based on feedback from Phase 2
  • make resources freely available

Where is the study up to?

Subscribe to receive more updates on this study (below) and also check out the study updates and progress page for the latest.

Right now, Phase 1 – a national wide survey and focus groups is underway. If you are interested in participating a survey or focus group, more information can be found here.


Keep up to date

Subscribe to receive email updates about the HAPPEN study. Don’t worry, these will be infrequent, but will keep you updated on key developments. Enter your email below. We also have a very popular podcast on infection control, called Infection Control Matters, with 60K+ listens from over 130 countries. You can find it on your favourite podcast provider.